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The 2020 Xenopus Community White Paper is now available!
PIs: Please reference the White Paper in your NIH grant proposals and contact your program officers.
Gurdon et al., published in PNAS, show that long-term (hours to days as opposed to seconds) non-competitive binding of transcription factors such as neurogenic Ascl1 stabilizes gene expression.
Willsey & Xu et al., using X. tropicalis, show that mutations in the neurodevelopmental disorder risk gene, dyrk1a, disrupts cell cycle progression and ciliogenesis causing brain defects. Published in Development.
Xenopus, from basic biology to disease models in the genomic era
Abraham Fainsod and Sally Moody are seeking contributions for a book to be published by Taylor and Francis CRC Press.
Please communicate your interest to them by May 15, 2020 and prepare to submit your contributions by January 2021.
Esmaeili et al. published in Developmental Biology their ATAC-seq study assessing chromatin accessibility during Xenopus gastrulation.
Processed ATAC-seq data viewable on JBrowse coming soon.